Acetaminophen, the active ingredient contained in many medicines and famous, is used for a long time as a febrifuge. Its
use, however, also extend to the sphere of pain: it acts as a
painkiller, alleviating disorders is "simple" as the headaches that most
forms of acute pain, in combination with other drugs (such as NSAIDs
and opioid analgesics).
It is considered a safe drug at the recommended doses, however, can lead to serious liver damage (even if you follow the prescription), especially if combined with alcohol -> root cause of drug overdose and liver failure in the West.
I think it's worth stopping for a moment the fact that paracetamol is derived from coal tar.
After this pause, continue by listing the pros and cons.
Paracetamol does not irritate the gastric wall, affects the clotting and does not impair renal function, BUT an use as "solid" results in a decrease in calcification of the kidneys and, in addition to possible gastric bleeding. But it can be used during pregnancy and childhood.
In 2008, The Lancet, a leading medical journal, has published an interesting study: administration of paracetamol to a sample of 200000 children in 31 different countries, revealed a higher incidence of asthma attacks in children 6-7 years and rhinoconjunctivitis and eczema in children of 1, 6 and 7 years.
Many "mysterious" doubts have arisen about the veracity of these data, so that the regulating organ of the United Kingdom, the Medicines and Healthcare products Regulatory Agency, wrote:
The results of this new research does not bring out the need for any change in the therapeutic indications for use in children. Paracetamol is an analgesic safe and appropriate for children. This research does not provide sufficient evidence that lead us to modify the instructions on the use of antipyretics for children.
They confirmed, however, the liver and kidney damage of this active ingredient.
Dosage: according to the Pharmacopoeia of the United States, the maximum dose should not exceed Day 4000mg per day (with a single dose not exceed 1000mg), while according to the Italian Pharmacopoeia, the maximum dose is 2600mg per day, with the appropriate reductions in dosing in subjects with renal impairment.
Nevertheless, it is considered a first-line drug to combat chronic pain.
It is considered a safe drug at the recommended doses, however, can lead to serious liver damage (even if you follow the prescription), especially if combined with alcohol -> root cause of drug overdose and liver failure in the West.
I think it's worth stopping for a moment the fact that paracetamol is derived from coal tar.
After this pause, continue by listing the pros and cons.
Paracetamol does not irritate the gastric wall, affects the clotting and does not impair renal function, BUT an use as "solid" results in a decrease in calcification of the kidneys and, in addition to possible gastric bleeding. But it can be used during pregnancy and childhood.
In 2008, The Lancet, a leading medical journal, has published an interesting study: administration of paracetamol to a sample of 200000 children in 31 different countries, revealed a higher incidence of asthma attacks in children 6-7 years and rhinoconjunctivitis and eczema in children of 1, 6 and 7 years.
Many "mysterious" doubts have arisen about the veracity of these data, so that the regulating organ of the United Kingdom, the Medicines and Healthcare products Regulatory Agency, wrote:
The results of this new research does not bring out the need for any change in the therapeutic indications for use in children. Paracetamol is an analgesic safe and appropriate for children. This research does not provide sufficient evidence that lead us to modify the instructions on the use of antipyretics for children.
They confirmed, however, the liver and kidney damage of this active ingredient.
Dosage: according to the Pharmacopoeia of the United States, the maximum dose should not exceed Day 4000mg per day (with a single dose not exceed 1000mg), while according to the Italian Pharmacopoeia, the maximum dose is 2600mg per day, with the appropriate reductions in dosing in subjects with renal impairment.
Nevertheless, it is considered a first-line drug to combat chronic pain.
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